Therefore, we selected the relevant markers such as age, gender, smoking habits (general character), BMI, WHR (obesity), SBP, DBP (hypertension), TG, TC (lipid metabolism), FG (glucose metabolism), hs-CRP (inflammation), AST, ALT, ALB, bilirubin, ALP, γ-GT, INR (liver reserve function), hemoglobin (oxidative stress), platelets, WBC, creatinine, UA, and ferritin (risk factors). The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.