Univariate and multivariate Cox regression analysis showed no significant effect of TNFA-308 G>A, NFKB1 -94ATTG ins/del, NFKBIA (-826 C>T and 3’UTR A>G) polymorphisms on the survival outcome of ESCC patients (Table 3 and 4). Here, TNF is linked to esophageal squamous cell carcinoma.