ANGPTL4 and Insulin resistance: This hypothesis is supported by our previous observation that neonates born by spontaneous delivery from pregnant women with gestational diabetes mellitus, with significantly higher concentrations in cord blood of cortisol (unpublished results), NEFAs and estimated insulin resistance (HOMA-IR) [47] than those found in neonates from control pregnant women, also showed a significantly higher concentration of ANGPTL4 in cord serum.