The number of TUNEL-positive cells in the tumor sections of the 5-FU-treated groups was also greater than that of the untreated control group (Figure 4), and was significantly correlated with 99mTc-C3(BHam)2-annexin A5 uptake or 99mTc-HYNIC-annexin A5 uptake in tumor tissue (Figure 5). Here, ANXA5 is linked to neoplasm.