However, the up-regulation of DLGAP5 positively correlated (P<0.05) with the level of alpha-fetoprotein (AFP) (P=0.036), the presence of portal vein tumor thrombus (PVTT) (P=0.015) and postoperative recurrence (χ2=4.255, P=0.039, Table 1). The gene discussed is DLGAP5; the disease is neoplasm.