Despite this finding, the up-regulation of DLGAP5 was not statistically correlated with gender, age (≥50 or <50), tumor size (≥5 or <5 cm), family history, hepatitis B surface antigen (HBsAg) expression, presence of liver cirrhosis, history wine-drinking, history of smoking, BCLC stage, or presence of distant metastasis or lymph node metastasis (P>0.05, Table 1). The gene discussed is DLGAP5; the disease is neoplasm.