To map the Mina promoter, a ∼2 kb-fragment spanning the transcriptional start site (TSS) from position −1588 to +354 was cloned into PGL3 basic vector and tested for reporter activity by dual luciferase assay in the thymoma cell line EL4 (Fig. 1, gray filled arrow). The gene discussed is RIOX2; the disease is thymoma.