Given this mechanism, we suggested that the following molecular functional chain could exist in ovarian cancer tissue: MUC2 (ovarian cancer cells) → MSR1 (TAMs) → COX-2 (TAMs) → PGE2 (TAMs) → EP2 (ovarian cancer cells) → COX-2 (ovarian cancer cells) → PGE2 (ovarian cancer cells). Here, PTGS2 is linked to ovarian cancer.