PTGS2 and cancer: The multivariate Cox regression analysis showed that the level of MUC2 expression in the cancer cells, peritoneal metastasis, cancer stage, histotype and grade, the size of residual site, the M1/M2 ratio of the TAMs and the densities of COX-2+ TAMs and COX-2+ cancer cells were independent prognostic factors for ovarian cancer patient outcomes (Table 3).