Because various inflammatory cytokines are known to mediate inflammation and are highly expressed in AD patients [5], we first assessed the effects of 7,3′,4′-THIF (Figure 1(b)) and daidzin (Figure 1(a)) on LPS-induced NO, TNF-α, and IL-6 production in RAW 264.7 cells. This evidence concerns the gene TNF and Alzheimer disease.