Among the 13 genes in the inferred RXRB-causal network, stepwise logistic regression identified a six-gene model (MDH2, RXRB, FABP1, ACADM, APOA5 and PPARG) as the most predictive model of lymph node metastasis. The gene discussed is RXRB; the disease is metastatic malignant neoplasm in the lymph nodes.