PMP22 and glioblastoma: For instance, the PMP22 gene was found to be amplified in two glioblastoma cell lines and an unusual transcript was found in the cells [29], PMP22 mRNA was higher in pancreatic adenocarcinomas than in normal tissue and was detected in cell lines [30], and high PMP22 mRNA in tumors correlated to poorer survival of breast cancer patients [31].