However, although the levels of EGFR mRNA and protein were increased in non-mutated and BRCA2-mutated ovarian cancer compared with their adjacent normal tissue, there was no significant difference in the expression of EGFR between the non-mutated and BRCA2-mutated groups, including ovarian cancer and normal ovarian tissue (Figure 1C and D). The gene discussed is BRCA2; the disease is ovarian cancer.