BRCA1 and ovarian carcinoma: However, although the expression of EGFR was also increased in ovarian cancer tissue (Figure 2I, P < 0.05) along with no significant difference in BRCA1 promoter methylation or expression (Figure 2G and H, P > 0.05), the increased levels of EGFR was not significant compared with ovarian cancer with BRCA1 deficiency.