LDLR and familial hyperaldosteronism: More than 1,288 different variants in the LDLR gene have been reported in FH patients as follows: 55% exonic substitutions, 22% exonic small rearrangements (<100 bp), 11% large rearrangements (>100 bp), 2% promoter variants, 10% intronic variants, and 1 variant in the 3′ untranslated sequence [68].