In the anti-VEGF antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in AMD (ANCHOR) study, which compared PDT with ranibizumab, a mean reduction of 9.8 letters was found in the PDT arm compared to a gain of 8.1 to 10.7 letters in the ranibizumab arm, validating the effectiveness of ranibizumab as a therapy for the improvement of vision in patients with neovascular AMD [11]. Here, VEGFA is linked to age-related macular degeneration.