First functional data were provided by Groux-Degroote et al. [33], who showed that IL-6 and IL-8 have stimulatory effect on expression of FUT11, and FUT11 may be involved in the biosynthesis of sialyl-Lewisx and 6-sulfo-sialyl-Lewisx epitopes in the bronchial mucins in inflammatory mucosae of cystic fibrosis patients. This evidence concerns the gene CXCL8 and cystic fibrosis.