We found that the percentage of DC in spleen, characterized by CD11c + expression, was significantly increased in LF-MF normal mice (9.57% of spleen lymphocytes) and sham LF-MF tumor-bearing mice (9.75% of spleen lymphocytes), compared with the sham normal mice (7.03% of spleen lymphocytes). The gene discussed is ITGAX; the disease is neoplasm.