LGALS3 and congestive heart failure: Patients were divided into three groups according to the change in LVEDV: decrease in LVEDV > 8%, stable LVEDV (−8–8%) and an increase in LVEDV > 8%. Plasma Gal-3 is associated with left ventricular remodeling determined by serial echocardiography and predicts long-term mortality in patients with severe chronic heart failure [27].