Subsequent studies have shown that these peptides bind only poorly to human class II HLA molecules commonly found in patients with MS, including DR2 (DRB1*15 : 01; DRB5*01 : 01), DR3, and DR4 [99], which likely explains this lack of responsiveness, although a recent study using HLA transgenic mice suggests that PLP139–151 can be presented by DQB1*06 : 02 [126]. Here, TNFRSF10A is linked to myeloid sarcoma.