IL-17 was not detected in our samples, possibly due to the early stage of infection [39], and IL-22 levels were not affected by NLRP3 or IL-1 β on DPI 6 or 10, as peak levels are typically noted at 4 days, and dissipate by 6 DPI, as observed by other investigators [59]. The gene discussed is NLRP3; the disease is infection.