Other independent parameters in univariate analysis were negative hormone receptor status (OR 4.2, 95% CI 2.4–7.6, p<0.001), tumor grade (G3 vs. G1–G2, OR 3.3, 95% CI 1.9–6.0, p<0.001) and negative nodal status (OR 2.0 CI 95% 1.1–3.5, p = 0.02). The gene discussed is NR4A1; the disease is neoplasm.