Added predictive capacity of log GDF-15 for 10 years outcome concerning total mortality, cardiovascular mortality (CVD), coronary heart disease mortality or morbidity (CHD), stroke mortality or morbidity and the composite of the former events (values are c statistics, category-free net reclassification improvement (NRI) and integrated discrimination improvement (IDI) for models without and with GDF-15 (c1 and c2 for models without GDF-15 and models with GDF-15, respectively)). This evidence concerns the gene GDF15 and stroke disorder.