The genotype-phenotype correlation of TNFA, CTLA4, IL4, MYG1, IFNG and NALP1 gene polymorphisms supported the autoimmune pathogenesis of vitiligo in Gujarat population [18], [76]–[80]; whereas our earlier studies on CAT, MBL2, ACE, PTPN22 polymorphisms did not show significant association [81]–[84]. This evidence concerns the gene PTPN22 and vitiligo.