In some hematopoietic malignancies, inactivating mutations of p53 are involved with chromosomal instability and progression towards acute leukemia, such as complex karyotype myelodysplastic syndromes[3], [4], [5], [6] and chronic phase Philadelphia-chromosome positive chronic myeloid leukemia (CML)[7]. Here, TP53 is linked to myelodysplastic syndrome.