Since ASPP2 expression can be induced by cellular damage to promote apoptosis[19], [23] and low ASPP2 levels are associated with poor-risk AML with early CR-failure (Figure 1), we wished to explore if ASPP2 levels correlate with leukemia cell sensitivity to daunorubicin-induced apoptosis. Here, TP53BP2 is linked to acute myeloid leukemia.