SUFU and chondrosarcoma: Moreover, germline or somatic mutations in the SUFU gene have recently been described in association with meningioma and chondrosarcoma (Aavikko et al., 2012 ▶; Kijima et al., 2012 ▶; Tarpey et al., 2013 ▶), again involving tissue types in which HH signalling is known to play a central role in normal development.