FCGBP and adenoma: The ratio of positive FcGBP expression was significantly down-regulated in gallbladder adenocarcinoma (48.1 %) than in peritumoral tissues (76.1 %), adenoma (80.0 %), polyps (86.7 %) and chromic cholecystitis (85.7 %) (P < 0.05) (Supplement Table 3).