In summary, the significant higher presence of the variant allele I249 in homo- and heterozygosis found in controls (91%) and in AMI survivors (94%), with respect to the patients died of AMI (48%), showed the relevance of this polymorphism both in the onset and outcome of acute myocardial infarction, confirming the correlation between CX3CR1 genotype and prognosis of the acute event. This evidence concerns the gene CX3CR1 and myocardial infarction.