Since bioinformatical analysis showed that HOXD10 was a putative target of miR-23a (Fig. 2A) and deregulation of HOXD10 was found to be associated with malignant tumors, we speculated that HOXD10 might be involved in the miR-23a mediated biological processes of glioma cells. Here, HOXD10 is linked to central nervous system cancer.