Due to the high therapeutic efficacy of the anti-CCR7 mAb described in this section, the potential of the antibody was further studied in a post-implantation disease model in which surviving Granta-519 MCL cells might have already migrated to their target organs and be less exposed to the anti-CCR7 treatment, thus better representing a clinical scenario in humans. Here, CCR7 is linked to mantle cell lymphoma.