TKTL1 and metastatic malignant neoplasm in the lymph nodes: TKTL1 expression was significantly associated with tumor size (pT3/4, p = 0.0018), advanced tumor stages (UICC III/IV, p < 0.0001), cervical lymph node metastasis (pN1-3, p = 0.0008), and extracapsular spreading of lymph nodes (p = 0.0099).