TKTL1 and cancer: OSCC tumors negative for Apo10 and TKTL1 represented tumors with favourably prognostic impact on survival, Apo10 presence indicated malignant OSCC tumors, and Apo10+/TKTL1+ OSCC tumors turned out to be more malignant tumors with an invasive/metastasing phenotype and worst prognostic impact on survival.