Hence four of the five proteins levels weresignificantly different between survivors and non-survivors and not related to the sepsis severity.Levels of FOXO1 and ACVR2A were differentially expressed among patients with sepsis, severe sepsisand septic shock, and the reason might be that some of these patients suffered from acute or chronicliver or kidney failure. The gene discussed is FOXO1; the disease is Sepsis.