Only few studies have investigated the effect of training on insulin sensitivity in patients with HIV-associated lipodystrophy, and conflicting results exist (Jones et al. 2001; Smith et al. 2001; Yarasheski et al. 2001; Thoni et al. 2002; Driscoll et al. 2004; Dolan et al. 2006; Robinson et al. 2007). Here, INS is linked to lipodystrophy.