The ICAM-1 mRNA expression level and the concentration of sICAM-1 in the supernatants of the cells treated with tulobuterol (0.1 μmol/L) plus ICI 118551 (1 μmol/L) were significantly higher than those in the cells treated with tulobuterol (0.1 μmol/L) alone and did not differ from the expression level and concentration in the cells treated with vehicle before RV14 infection (Fig. 3A and B). The gene discussed is ICAM1; the disease is infection.