For example, miR-27a and miR-451 are activators of MDR1/P-gp expression in the development of MDR in human ovarian and cervical cancer cells [14] while miR-451 negatively regulates the expression of the MDR1 gene in the multidrug-resistant breast cancer cell line, MCF7/DOX [15]. Here, ABCB1 is linked to cervical carcinoma.