As reviewed by Kinast et al. (2013) the cognitive (PFC-dependent) and somatosensory phenotypes observed in 5-HTT knockout rodents as well as human subjects carrying the low activity variant of the serotonin transporter linked polymorphic region (5-HTTLPR) strikingly resemble those seen in autistic patients, rats prenatally treated with VPA (rat model for autism), and human and rodent subjects prenatally exposed to SSRIs (see also Olivier et al., 2013) (Figure 1). The gene discussed is SLC6A4; the disease is autism.