Biological functions that were uniquely affected in the intestine during zinc deficiency included ‘cellular assembly and organisation’, which was comprised of several child functions such as ‘assembly of mitotic spindle’ (CKAP5, HDAC3, TNKS; p < 1.6 × 10–4), ‘organization of cytoplasm’ (APOE, ARPC5, ATL2, CKAP5, EFNA3, ELMO1, ITGB1, RBBP4, SYNE1, TNKS; p < 1.6 × 10–4; z = –1.82) and ‘organization of organelle’ (ATL2, CKAP5, ITGB1, RBBP4, SYNE1, TNKS; p < 6.5 × 10–3). The gene discussed is SYNE1; the disease is Zinc deficiency.