For diabetes type 2, one study among patients aged on average 59 years reported that most patients (61.9%, n = 1133) received oral antidiabetic drugs monotherapy, followed by insulin and oral antidiabetic drugs (OAD) (19.4%, n = 356), insulin monotherapy (17.3%, n = 317), no treatment (1.1%, n = 20), and herbal treatment (0.3%, n = 5) [26]. Here, INS is linked to type 2 diabetes mellitus.