ERBB2 and breast cancer: We utilized a cohort of 70 primary human breast cancers of known clinical classification representing each of the intrinsic molecular subtypes (36 luminal A-like, 13 luminal B-like, 5 Her2-enriched and 16 basal-like) and 18 normal mammoplasty tissues to analyze expression of microRNAs that contribute to regulation of DNMT3b. Average miR expression for breast cancers reflecting each of the clinical classifications is shown in Table I.