Thus, as it could be expected, when anti-SSA/Ro60 and anti-Ro52/TRIM21 were separately analysed, the association became statistically significant both for photosensitivity (OR 2.35, CI 95% 1.12–4.96, P = 0.024 and OR 2.75, CI 95% 1.13–6.71, P = 0.026 for, resp., anti-SSA/Ro60 and anti-Ro52/TRIM21) and xerophthalmia/xerostomia (OR 2.57, CI 95% 1.16–5.68, P = 0.019 and OR 2.62, CI 95% 1.15–5.99, P = 0.022 for, resp., anti-SSA/Ro60 and anti-Ro52/TRIM21). This evidence concerns the gene TRIM21 and xerostomia.