According to the World Health Organization (WHO) 2008 classification [1, 2], acute myelogeneous leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic myelogenous leukemia (CML) are categorized by the presence of specific balanced chromosomal translocations: AML is associated with t(8;21)(q22;q22), inv(16)(p13q22) or t(16;16)(p13;q22), t(15;17)(q22;q12), and 11q23/MLL abnormalities; ALL is mainly associated with t(12;21)(p13;q22), t(9;22)(q34;q11.2), and t(1;19)(q23;p13); and CML is characterized by the Ph+ chromosome or t(9;22)(q34;q11.2). This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.