Finally, although cell cocultures from patients with RA and SLE tended to show an increased generation of Th1/Th17 lymphocytes (CD4+ IL-17A+ IFN-γ+), no significant differences were observed when compared to cells from healthy controls (P > 0.05 in all cases, Figure 3(b)). This evidence concerns the gene IL17A and systemic lupus erythematosus.