Compared to the inconclusive adiponectin-asthma studies [55, 64, 65], the US-based longitudinal cohort [69] possibly had a greater statistical power due to both a planned selection of large numbers of African Americans as well as a fortuitous selection of large numbers of obese subjects and smokers—these population groups are known to be particularly associated with low serum total adiponectin concentrations [14]. Here, ADIPOQ is linked to asthma.