PPARD and chronic kidney disease: When those with at least one minor allele of each PPAR SNP were combined together and compared with the references (subjects with homozygous major allele) (dominant model), those with PPARD T-842C T/C + C/C demonstrated the significantly increased risk of CKD with the aORs of 1.27 (1.05–1.53), while no other SNP turned out to be significant in this analysis (Table 2).