It is also reported that common polymorphisms in PPARD gene were associated with fasting glucose, insulin resistance, and risk of conversion from impaired glucose tolerance to type 2 diabetes in Europeans [28], and some functional variants in PPARD gene were reportedly associated with fasting glucose and BMI in Koreans [29] and fasting glucose levels and insulin sensitivity in Chinese [30, 31]. Here, INS is linked to Impaired glucose tolerance.