Also, Sam68-like mammalian proteins (SLM-1 and SLM-2), the heterogeneous nuclear ribonucleoproteins hnRNP A2/B1 and hnRNP G, the splicing factor YT521 [87], Sik/BRK [41] and more recently, the splicing repressor hnRNP L [88], have been described to interact with Sam68 in SNBs, thus suggesting a role for these organelles in coupling signaling to RNA processing in cancer cells. Here, KHDRBS1 is linked to cancer.