Similarly, for the group in which there were changes in DECT urate volume above the SDC, the change in DECT urate score correlated with changes in the frequency of gout flares (r = 0.41, P = 0.037), but not with changes in subcutaneous tophus count, C-reactive protein, HAQ-II score, tender joint count or swollen joint count (r < 0.29, P > 0.15 for all). This evidence concerns the gene CRP and gout.