Therefore, in spite of having a moderate effect on CAD as compared to other genetic variants described by Schunkert et al., such as polymorphisms in CDKN2A, SORT1, LDLR, MRPS6 and MIA3[9], we assessed this time the ZC3HC1 rs11556924 polymorphism because we had already analyzed the potential role of some others. The gene discussed is CDKN2A; the disease is coronary artery disorder.