used the System for Integrative Genomic Microarray Analysis (SIGMA [32]) to evaluate genetic loss or gain of CSN6 (located at 7q22.1) using data from the British Columbia Cancer Agency Research (BCCRC) SMRT arrays, and found that a substantial percentage of samples (breast cancer cell lines and other types of cancer cells) had amplification of the CSN6 genomic region. The gene discussed is COPS6; the disease is breast cancer.