EGFL7 and systemic sclerosis: A trend toward reduction in the circulating levels of EGFL7 was observed in SSc patients with digital ulcers (median 0.0 ng/ml, IQR 0.0 to 2.2 ng/ml) compared with those without digital ulcers (median 0.6 ng/ml, IQR 0.0 to 8.0 ng/ml; P = 0.08).