EGFL7 and systemic sclerosis: EGFL7 levels were lower in SSc patients with late NVC pattern (median 0.0 ng/ml, IQR 0.0 to 2.7 ng/ml) than in those with early (median 0.6 ng/ml, IQR 0.0 to 6.2 ng/ml) or active (median 0.0 ng/ml, IQR 0.0 to 7.1 ng/ml) patterns, but these differences did not reach statistical significance (Figure 1B).