Deletions at chromosome 22 or loss of SMARCB1/INI1 expression have also been implicated in the pathogenesis of additional tumor types: renal medullary carcinomas, epithelioid sarcomas, myoepithelial carcinomas and extraskeletal myxoid chondrosarcomas [7]. The gene discussed is SMARCB1; the disease is kidney medullary carcinoma.