SUV39H2 is a gene that encodes histone methyltransferase which catalyzes the methylation of H3K9, and recent results from the Finnish Diabetic Nephropathy Study with ~3000 diabetic patients have found an association between the polymorphism in SUV39H2 and diabetic microvascular complications, including retinopathy. Here, SUV39H2 is linked to retinal disorder.