ASGR1 and hepatocellular carcinoma: Jeong et al. [38] synthesized the poly(gamma-benzyl L-glutamate) (PBLG)/poly(ethylene glycol) (PEG) diblock copolymer endcapped with galactose moiety and characterized for study of liver specific targeting and concluded that HepG2 cells with ASGP-R are more sensitive to TX-loaded nanoparticles than free TX, whereas P388 cells, murine leukemia cell line, and SK-Hep 01, human hepatoma cell line, without ASGP-R are less sensitive to TX-loaded nanoparticles than free TX, suggesting that specific interaction between HepG2 cells and galactose moiety of the nanoparticles occurred.