Moreover, the ICU mortality rates of septic patients with CRP concentrations <10, 10–20, 20–30, 30–40 and >40 mg/dL were 20%, 34%, 30.8%, 42.3%, and 39.1%, respectively, P = 0.7, and the area under the curve for CRP to diagnose an infection was 0.55 (0.45–0.65), no better than leukocyte count or temperature. Here, CRP is linked to infection.